We all know vitamin D as the sunshine vitamin, and that it is important for bone and muscle development and helps prevent osteoporosis. However, it has multiple functions beyond its widely recognized role in regulating calcium levels and bone metabolism.
Vitamin D receptors are found in more than 30 cell types and the research focus recently has shifted from bone health to vitamin D’s effect on cancer, cardiovascular health and weight loss, among other health issues. Latest studies reveal the close link between adequate vitamin D levels and chronic pain.
One such study compared vitamin D levels in patients with fibromyalgia, rheumatoid arthritis and osteoarthritis. These patients were found to have lower levels of vitamin D than the normal population. In addition, patients with fibromyalgia had the lowest levels compared to the other two groups.
To test their theory that a vitamin D deficiency contributed to pain and fatigue, researchers gave the three groups 3 intramuscular injections of cholecalciferol every four weeks. After treatment, patients in all three groups reported lower levels of fatigue and pain.
In another study, researchers found that vitamin D supplementation, along with weight loss, has a greater effect on reducing chronic inflammation than weight loss alone. Chronic inflammation is known to contribute to the development and progression of several diseases, including some cancers.
Lead author Dr Catherine Duggan. from the Fred Hutchininson Cancer Research Centre in the US, said: "We know from our previous studies that by losing weight, people can reduce their overall levels of inflammation, and there is some evidence suggesting that taking vitamin D supplements can have a similar effect if one has insufficient levels of the nutrient."
This time, they looked at more than 200 overweight, postmenopausal women who had insufficient levels of vitamin D. The women then took part in a 12-month diet and exercise program (including 45 minutes of moderate-to-vigorous exercise five days a week). Half of the study participants were randomly selected to receive 2,000 IU of vitamin D daily for the duration of the year-long trial, and the other half received an identical-appearing placebo.
At the end of the study, all of the participants had reduced levels of inflammation, regardless of whether they took vitamin D, “which highlights the importance of weight loss in reducing inflammation,” Dr Duggan said. However, those who saw the most significant decline in markers of inflammation were those who took vitamin D and lost 5 to 10 percent of their baseline weight.
Vitamin D: How to get enough naturally
Vitamin D is found in small amounts in foods like fish, eggs and mushrooms. During summer time, you need just 5 minutes - 15 if you have dark or olive skin tones - of sun exposure to your face, arms and hands (or equivalent) to get your dose of vitamin D. Over winter, you need 2 to 3 hours of sun exposure for those with fair skin and triple that for those with darker complexions.
Inflammation is our body's response to injury or foreign substances. Now, latest research shows that depression may also be the body's reaction to inflammation. According to Nova Next, people suffering from depression are loaded with cytokines, which is the same substance produced during inflammation.
So, how does it link up? Some researchers think the inflammatory response could be spurred by an infection of some kind. Others regard obesity or modern high-trans-fat, high-sugar diets as the cause. Still others say that emotional stress from bullying, rejection, or loneliness is transformed into a physical stress, then causing a changed emotional state.
Whatever the ultimate cause, it is beneficial to explore treatments that tackle the inflammatory symptoms of depression in addition to the neurological ones. The few clinical trials done so far found that adding anti-inflammatory medicines to antidepressants not only improves symptoms, it also increases the proportion of people who respond to treatment, although more trials will be needed to confirm this.
There is also some evidence that omega 3 and curcumin, an extract of the spice turmeric, might have similar effects but there’s not enough evidence to use them as a replacement for anti-depressants. You can find really good formulations of these supplements at Simply Well, but please speak to one of our practitioners first to make sure it is appropriate for you.
There are plenty of organisations like Beyond Blue that can help if you or someone you know suffers from depression.
All entries complied by osteopath Dr Wei Chua unless otherwise stated.